Dataset of PTP1B extra hits
If you are simply looking for the PTP1B extra hits referenced in the cluster4x paper then please download them from this link.. The smaller number of hits from the three original PanDDA studies is also available.
Downloading cluster4x
On most flavours of Linux, you can easily download cluster4x directly using snap.
On Mac OS X (minimum version 10.14), a pre-compiled binary is available.
Cluster4x
Cluster4x looks at multi-datasets and partitions data into datasets which behave in similar ways. It is interactive, allowing you to fully explore your data set. It can compare your datasets using amplitude differences or C-alpha atom positions.
Cluster4x is often used to increase the power of PanDDA to find hits in your dataset. Often pre-clustering with PanDDA will lead to more hits in your datasets. The published paper shows an increase in the hit rate by over 65% when re-analysing the published data for a PTP1B fragment screen.
